N-Iodosuccinimide

N-iodosuccinimide (NIS) is a reagent in organic chemistry for alkene iodination and a gentle oxidant. It is the iodine counterpart of N-chlorosuccinimide (NCS) and N-bromosuccinimide (NBS), employed in analogous applications.

Properties Of N-Iodosuccinimide

Appearance	White solid
Density	2.245 g/cm3
Melting point	202–206 °C (396–403 °F; 475–479 K)(dec.)
Solubility in water	Soluble in Dioxane, THF, MeCN; Insoluble in ether, CCl4

Applications of N-Iodosuccinimide

• Halogenation Reactions: N-Iodosuccinimide is commonly used as a mild iodinating agent for the selective halogenation of organic compounds, particularly in aromatic and allylic substitution reactions. It facilitates the introduction of iodine atoms into organic molecules with high regioselectivity and functional group tolerance.
• Oxidation Reactions: NIS can serve as an oxidizing agent in certain oxidation reactions, leading to the conversion of primary alcohols to aldehydes and secondary alcohols to ketones. This mild oxidation method finds applications in organic synthesis and functional group transformations.
• Substitution Reactions: NIS can promote substitution reactions, including nucleophilic substitution and radical substitution, leading to the formation of iodinated derivatives of organic compounds. It is particularly useful for the preparation of iodinated intermediates in complex molecule synthesis.
• Photocatalysis: N-Iodosuccinimide has been employed as a photocatalyst in certain organic transformations, facilitating photochemical reactions under mild conditions. This application expands the scope of NIS in synthetic methodology development.
• Medicinal Chemistry: NIS derivatives and iodinated compounds synthesized using NIS find applications in medicinal chemistry, particularly as radiolabeled probes and imaging agents for positron emission tomography (PET) and single-photon emission computed tomography (SPECT).

Packaging Options

• Drums

Safety Guidelines

Emphasizing safety is crucial in any workplace dealing with chemical substances, whether they are hazardous or non-hazardous. Familiarize yourself with the properties, potential risks, and proper handling procedures for each chemical encountered. For comprehensive information, consult the Safety Data Sheets (SDS) and Technical Data Sheets (TDS) provided by Relic Chemicals representatives.

When working with chemicals, prioritize safety, regardless of potential hazards. Adhere to established safety protocols, seek guidance in uncertain situations, and make the well-being of yourself and others the top priority.

Why Choose Us ?

Relic Chemicals, based in Mumbai, Maharashtra, has been a prominent manufacturer, distributor, and exporter in the chemical industry since 2015. Our expertise spans various sectors, including specialty chemicals, pharmaceuticals, oil and gas, pulp and paper, fire retardants, and agrochemicals.

Over the years, Relic Chemicals has established a track record of quality. Our constant performance and good client testimonials strengthen our reputation as a reliable and chosen partner in the chemical companies.

Your satisfaction is our top priority. Relic Chemicals has a customer-centric strategy, adapting our services to your needs. Our attentive and dedicated team guarantees that your concerns are addressed quickly, building an engaging and long-lasting connection.