N-Bromosuccinimide or NBS is a chemical reagent used in radical substitution, electrophilic addition, and electrophilic substitution reactions in organic chemistry. NBS can be a convenient source of Br•, the bromine radical. N-bromosuccinimide (NBS) is a cyclic chemical compound with a five-membered ring structure containing two carboxamide groups and a bromine atom attached to nitrogen. Its molecular formula is C4H4BrNO2 with a Molecular weight 177.9g/mol. n.
Relic Chemicals is a comprehensive global manufacturer, supplier, and exporter from Mumbai, Maharashtra, India, specializing in N-Bromosuccinimide (NBS). We are dedicated to providing distinctive product options that meet the highest quality requirements.
N BromoSuccinimide (NBS) properties
Item | Standard |
Appearance | Off White to light yellow powder |
Assay | NLT 95 % w/w, on dried basis |
Melting Point | Between 178 °C to 188 °C. |
Loss on Drying (w/w) (600C under vacuum for 3 hrs) | Not more than 0.5 % w/w |
Solubility | Sparingly soluble in methanol, Soluble in Acetone, Glacial Acetic Acid & Alkali Hydroxide |
Residue on Ignition | Not more than 0.1% w/w |
Other Names Of N BromoSuccinimide
Uses of N BromoSuccinimide (NBS) Reagent
- Allylic Bromination
- NBS is often used in the bromination of allylic places in chemical compounds. It selectively attaches a bromine atom to the allylic carbon, making it an effective reagent in the production of allylic bromides.
- Bromination of Alkenes
- Alkenes may undergo bromination reactions in the presence of NBS. The bromine atom is inserted at the double bond, allowing for selective bromine addition to unsaturated hydrocarbons.
- Modification of Proteins
- NBS has biochemical applications, such as selectively brominating specific amino acid residues in proteins. Tryptophan and histidine are frequently targeted in these protein changes.
- Preparation of Bromohydrins
- NBS is utilized in the production of bromohydrins from alkene. In this reaction, bromine and hydroxyl groups are added to the carbon-carbon double bond.
- α-Bromination of Carbonyl Compounds
- NBS promotes the α-bromination of carbonyl compounds, including ketones and aldehydes. This reaction is essential in the production of brominated organic molecules.
Packaging Options
N-bromosuccinimide (NBS) is available in 50-kilogram drums as a packaging options.
Note: Samples are available upon request
Safety guidelines:
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When working with chemicals, prioritize safety, regardless of potential hazards. Adhere to established safety protocols, seek guidance in uncertain situations, and make the well-being of yourself and others the top priority.
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